Can anyone else see if thats whats going on in there games ?.
I've had no problems running the new build - but I'm running the standalone one, without using the Desura client, which I guess could work differently.
I've run into a couple of oddities when playing which might be related to your operative problems - although I am
able to plan, authorise, assign and start missions, and watch them play out. This is all using the starting four operatives.
I ran one initial mission where my operatives were successful. Hooray.
I then ran another mission with the same four operatives (in the same cell), and they failed - they fell foul of a challenge halfway through and all got shot and killed.
After that cell had been killed, I could not start any further missions (either with that cell with new operatives added to it, or after erasing that cell and creating a new one with new operatives). The mission gets to the stage where the Start button is available, but clicking it does nothing (lemonrev - sounds similar to your problem).
I haven't tried:
a) Doing nothing with my initial four operatives, simply hiring a couple of newbies and using THEM to run missions.
b) Leaving a dead/empty cell intact, creating a new one and assigning new operatives to that (i.e. using 'cell 2' rather than the defeated/rebuilt 'cell 1').
Couple of relevant screenshots:
Playing, watching a mission take place (and fail miserably
After the first team had all got killed, the second team's mission screen is locked at this point: http://i.imgur.com/tTaunxC.jpg